TY  - BOOK
AU  - Ward,Simon E.
AU  - Davis,Andrew M.
TI  - The handbook of medicinal chemistry: principles and practice 
SN  - 9781839165887
AV  - RS403 .H34 2023
U1  - 615.19 23
PY  - 2023///]
CY  - Cambridge
PB  - Royal Society of Chemistry
KW  - Pharmaceutical chemistry
KW  - Drug development
KW  - Drugs
KW  - Chemistry, Pharmaceutical
KW  - Pharmaceutical Preparations
KW  - Chimie pharmaceutique
KW  - M�edicaments
KW  - D�eveloppement
KW  - fast
N1  - Previous edition: 2015; Includes bibliographical references and index; Physicochemical Properties; Synthesis in Medicinal Chemistry; Useful Computational Chemistry Tools for Medicinal Chemistry; Structure-based Design for Medicinal Chemists; Fragment-based Ligand Discovery; Machine Learning in Drug Design; Drug Metabolism; ADME Optimization in Drug Discovery; Molecular Biology for Medicinal Chemists; Assays; In Vitro Biology: Measuring Pharmacological Activity That Will Translate to Clinical Efficacy; Animal Models: Practical Use and Considerations; Bioinformatics for Medicinal Chemistry; Translational Science; Discovery Toxicology in Lead Optimization; Toxicology and Drug Development; Patents for Medicines; Target Validation for Medicinal Chemists; Lead Optimisation: What you should know!; Pharmaceutical Properties -- The Importance of Solid Form Selection; The Medicinal Chemistry and Process Chemistry Interface; Clinical Drug Development; SMN2 Splicing Modification by Small Molecules -- A Blueprint to Tackle the Underlying Genetic Cause of Many Underserved Diseases; The Discovery of Checkpoint Kinase 1 Inhibitors: From Fragments to Clinical Candidate; Medicinal Chemistry for Neglected Diseases -- Malaria, Tuberculosis, Sleeping Sickness, Leishmaniasis and River Blindness; New Therapeutic Chemical Modalities: Compositions, Modes-of-action, and Drug Discovery
UR  - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3580101
ER  -