Magnetic nanoparticles in biosensing and medicine / edited by Nicholas J. Darton (Arecor Limited), Adrian Ionescu (University of Cambridge), Justin Llandro (Tohoku University).

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Cover; Half-title; Title page; Copyright information; Table of contents; List of contributors; Preface; List of abbreviations; 1 Magnetism, Magnetic Materials, and Nanoparticles; 1.1 Introduction; 1.2 Fundamental Concepts; 1.2.1 Quantum Mechanical Concepts; 1.2.2 Atomic Magnetic Moments; 1.2.3 Macroscopic Considerations; 1.2.4 Calculation of Atomic Susceptibilities; 1.2.4.1 Diamagnetism; 1.2.4.2 Paramagnetism; 1.2.4.3 Ferromagnetism and Antiferromagnetism; Susceptibility of Local Moments; Exchange Interactions; Magnons; 1.3 Magnetization Processes; 1.3.1 Magnetic Anisotropies

1.3.2 Magnetic Domains1.3.2.1 Domain Walls; 1.3.2.2 Magnetization Reversal; Magnetization Reversal in Thin Films and Particles; Magnetization Dynamics; 1.3.3 Magnetization of Nanoparticles; 1.4 Magnetic Measurements; 1.4.1 Magnetometers; 1.4.2 Dependence of the Magnetization on Temperature; 1.4.2.1 Spontaneous Magnetization; 1.4.2.2 Magnetocaloric Effect; 1.4.2.3 Arrott Plots; 1.4.3 Critical Phenomena; 1.4.3.1 Thermal Dependence of the Order Parameter; 1.4.3.2 Thermal Dependence of the Initial Susceptibility; 1.4.3.3 The Field Dependence of the Order Parameter along the Critical Isotherm

1.4.3.4 The Specific Heat1.4.3.5 The Thermal Variation of the Spin Density Fluctuations close to TC; 1.4.4 AC Susceptibility; 1.4.5 M�ossbauer Spectroscopy; 1.4.6 Neutron Scattering; 1.4.7 X-ray Magnetic Circular Dichroism (XMCD); 1.5 Structural Analysis; Sample Problems; References; 2 Preparation of Magnetic Nanoparticles for Applications in Biomedicine; 2.1 Introduction; 2.2 Fundamentals of Solution Routes and Some Interesting Examples; 2.2.1 Aqueous Co-Precipitation Routes; 2.2.2 Hot Organic Solvents; 2.2.3 Growth Under Confinement; 2.3 Nanocomposites from Solution Routes

2.3.1 Organic Matrices2.3.1.1 Polymer Matrices; 2.3.1.2 Liposomes and Micelles; 2.3.1.3 Nanogels and Solid Lipid Nanoparticles; 2.3.1.4 Metal-Organic Frameworks (MOFs); 2.3.2 Inorganic Matrices; 2.4 Gas and Solid Routes; 2.5 Conclusions and Perspectives; Sample Problems; References; 3 Magnetic Nanoparticle Functionalization; 3.1 Gold-Coated Particles; 3.1.1 SAM Monomers; 3.1.1.1 Tail Groups; 3.1.1.2 Chain; 3.1.1.3 Head Groups; 3.1.2 Mixed SAMs; 3.1.3 Fluorescence Quenching/Enhancement; 3.1.4 Chemical Suppliers; 3.1.5 Aside: Classical Photolithography; 3.1.6 Alternative Directions

3.2 Coupling to Epoxides3.2.1 Organic or Aqueous?; 3.2.2 Linkers; 3.2.3 Spacers; 3.2.4 Aldehydes/Tosyl; 3.3 Quantification; 3.3.1 Kaiser Test (for Primary Amines); 3.3.2 Spectrophotometry; 3.3.3 Fehling's Test (for Aldehydes); 3.3.4 Tests for Alcohols; Sample Problems; References; 4 Manipulation; 4.1 A Survey of Tweezers for the Manipulation of Micro/Nanoentities; 4.1.1 Optical Tweezers; 4.1.2 Magnetic Tweezers; 4.1.3 Electric Tweezers; 4.1.4 Optoelectronic Tweezers; 4.1.5 Catalytic Tweezers; 4.1.6 Acoustic Tweezers; 4.1.7 Plasmon Nano-Optical Tweezers; 4.1.8 Plasmonic Micro-Trapping

A comprehensive insight into the fundamentals of magnetic biosensors and the applications of magnetic nanoparticles in medicine.

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