The handbook of medicinal chemistry : principles and practice / edited by Simon E. Ward and Andrew M. Davis.

Print version record.

Previous edition: 2015.

Includes bibliographical references and index.

Physicochemical Properties; Synthesis in Medicinal Chemistry; Useful Computational Chemistry Tools for Medicinal Chemistry; Structure-based Design for Medicinal Chemists; Fragment-based Ligand Discovery; Machine Learning in Drug Design; Drug Metabolism; ADME Optimization in Drug Discovery; Molecular Biology for Medicinal Chemists; Assays; In Vitro Biology: Measuring Pharmacological Activity That Will Translate to Clinical Efficacy; Animal Models: Practical Use and Considerations; Bioinformatics for Medicinal Chemistry; Translational Science; Discovery Toxicology in Lead Optimization; Toxicology and Drug Development; Patents for Medicines; Target Validation for Medicinal Chemists; Lead Optimisation: What you should know!; Pharmaceutical Properties -- The Importance of Solid Form Selection; The Medicinal Chemistry and Process Chemistry Interface; Clinical Drug Development; SMN2 Splicing Modification by Small Molecules -- A Blueprint to Tackle the Underlying Genetic Cause of Many Underserved Diseases; The Discovery of Checkpoint Kinase 1 Inhibitors: From Fragments to Clinical Candidate; Medicinal Chemistry for Neglected Diseases -- Malaria, Tuberculosis, Sleeping Sickness, Leishmaniasis and River Blindness; New Therapeutic Chemical Modalities: Compositions, Modes-of-action, and Drug Discovery

WorldCat record variable field(s) change: 650