Paul's fundamental immunology /
Paul's fundamental immunology /
Fundamental immunology
[edited by] Martin F. Flajnik, Nevil J. Singh, Steven M. Holland.
- 8th edition.
- Philadelphia: Wolters Kluwer/Lippincott Williams & Wikins, 2023.
- xix, 1669p. : ill. (col.) ; 29 cm.
Includes bibliographical references and index.
Section I. Introduction to Immunology1 Overview of the Immune System — 1Martin F. Flajnik, Steven M. Holland, Nevil J. Singh2 History of Immunology — 29Edward J. Moticka Section II. Evolution of the Immune System3 The Insect Immune System — 52Sara Cherry, Nicolas Buchon4 Evolution of the Vertebrate and Lower Deuterostome Immune System — 79Martin F. Flajnik5 The Plant Immune System — 134Roger W. Innes Section III. Cellular Pathways and Processes in Immunity6 Immunometabolism — 161Jonathan D. Powell, Chirag H. Patel, Im- Hong Sun7 Regulated Cell Death in the Immune System — 204Douglas R. Green, Sebastian Ruehl8 Lymphoid Tissues and Organs — 228Martin F. Flajnik, Nancy H. Ruddle9 Type I Cytokines, Interferons, and Their Receptors — 258Achsah D. Keegan, Warren J. Leonard10 Tumor Necrosis Factor Superfamily of Cytokines and Receptors — 308Carl F. Ware, Nancy H. Ruddle11 Chemokines and Chemokine Receptors — 344Philip M. Murphy Section IV. Innate Immunity12 Pattern Recognition Receptors and the IL- 1 Family — 386Rajendra Karki, Thirumala- Devi Kanneganti13 The Complement System — 416Erin E. West, Claudia Kemper14 Neutrophils — 455Andres Hidalgo, Mariana J. Kaplan15 Macrophages — 469Gwendalyn J. Randolph16 Mast Cells and Basophils — 487Mindy Tsai, Stephen J. Galli17 Eosinophils — 519Elizabeth A. Jacobsen, Hirohito Kita18 The Biology of Natural Killer Cells and Innate Lymphoid Cells — 537Vincent Peng, Marco Colonna Section V. Adaptive Immunity19 The Major Histocompatibility Complex — 573David H. Margulies, Kannan Natarajan, Jamie Rossjohn, James McCluskey20 Classical Antigen Processing and Presentation — 622Jonathan W. Yewdell, Paul Roche, Laurence C. Eisenlohr21 Immunoglobulins: Structure and Function — 644Mohamed Khass, David Wald, Neil S. Greenspan, Harry W. Schroeder, Jr22 Immunoglobulins: Molecular Genetics — 671Sebastian D. Fugmann23 T Cell Antigen Receptors and Antigen Recognition — 702Mark M. Davis, Yueh- Hsiu Chien24 Antigen Receptor Signaling — 734Nevil J. Singh, Gideon Wolf 25 B Cell Development in Mice — 774Nicole Baumgarth26 B Cell Responses — 798Claude- Agnès Reynaud, Jean- Claude Weill27 T Cell Development in the Thymus — 823Avinash Bhandoola, Remy Bosselut, Yousuke Takahama28 CD4+ Helper T Cells: Differentiation, Flexibility, and Heterogeneity — 856John J. O’Shea, Marion Pepper, Marc K. Jenkins, Danielle A. Chisolm29 Regulatory T Cells — 874Ethan M. Shevach30 CD8+ T Cell Memory — 924Francis R. Carbone, Thomas Gebhardt31 Cytotoxic Effector Functions — 944Morgan Huse Section VI. Integrative Immunology32 Immunologic Tolerance — 971Colin C. Anderson, Troy A. Baldwin, Peter A. Bretscher33 Fc Receptors and Their Role in Immune Regulation and Inflammation — 1008Jeffrey V. Ravetch, Aaron Gupta, Falk Nimmerjahn34 Dendritic cells — 1034Roxane Tussiwand, Pierre Guermonprez, Simon Yona35 Gamma Delta T Cells — 1054Adrian C. Hayday36 CD1- Restricted T Cells — 1102Pankaj Sharma, Florian Winau37 Mucosal- Associated Invariant T Cells and Other MR1- Reactive T Cells — 1137Sidonia B. G. Eckle, Wael Awad, Jamie Rossjohn, James McCluskey, Alexandra J. Corbett38 The Mucosal Immune System — 1178Yasmine Belkaid, Brian L. Kelsall, Warren Strober39 Introduction to Neuroimmunology — 1212Andrea Francesca Salvador, Jonathan Kipnis40 Vaccines — 1231Bali Pulendran41 Maternal- Fetal Immunology — 1283Gabrielle Rizzuto, Adrian Erlebacher Section VII. Immune Responses to Pathogens42 Response to Parasites — 1325David Sacks, Marion Pepper, Mary F. Fontana, P’ng Loke43 Immune Responses to Bacteria — 1355S. Celeste Morley, Moon H. Nahm44 Response to Viruses — 1399Hildegund C. J. Ertl45 Immunology of HIV Infection — 1445Gaurav D. Gaiha, Douglas S. Kwon Section VIII. Immunological Disease States and Immunodeficiency46 Autoimmunity and Autoimmune Diseases — 1465Gustaf Christoffersson, Ken T. Coppieters, Matthias von Herrath, Dirk Homann47 Immunologic Mechanisms of Allergic Disorders — 1515Stéphanie Lejeune, Kari C. Nadeau, David W. Scott, Joshua D. Milner48 Transplantation Immunology — 1549Megan Sykes, Anita S. Chong, Markus Y. Mapara49 Cancer Immunology and Immunotherapy — 1589Thomas F. Gajewski, Justin Kline50 Inborn Errors of Immunity — 1619
"Selected as a Doody's Core Title for 2022!Defining the field of immunology for 40 years, Paul's Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It's an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Reflects the latest advances in the field, including current insights on immune system function, both basic and translational. Contains 50 chapters written by leaders in all subfields of immunology. Provides extensive coverage of the molecular biology that explains the dynamics underlying immune disorders and their treatment. Includes 10 entirely new chapters covering invertebrate and plant immunity, eosinophils, innate lymphoid cells, gamma/delta T cells, NKT and MAIT cells, immunometabolism, maternal-fetal immunology and more. Contains abundant full-color illustrations and tables that provide essential information at a glance. Features annual updates from the authors to the VST version, keeping you current with changes in this dynamic field from the experts. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. "--
9781975142513
2022032189
MEDICAL / Immunology
MEDICAL / Infectious Diseases
Immune System Phenomena
RC585 / .P38 2023
616.97
QW 504
Includes bibliographical references and index.
Section I. Introduction to Immunology1 Overview of the Immune System — 1Martin F. Flajnik, Steven M. Holland, Nevil J. Singh2 History of Immunology — 29Edward J. Moticka Section II. Evolution of the Immune System3 The Insect Immune System — 52Sara Cherry, Nicolas Buchon4 Evolution of the Vertebrate and Lower Deuterostome Immune System — 79Martin F. Flajnik5 The Plant Immune System — 134Roger W. Innes Section III. Cellular Pathways and Processes in Immunity6 Immunometabolism — 161Jonathan D. Powell, Chirag H. Patel, Im- Hong Sun7 Regulated Cell Death in the Immune System — 204Douglas R. Green, Sebastian Ruehl8 Lymphoid Tissues and Organs — 228Martin F. Flajnik, Nancy H. Ruddle9 Type I Cytokines, Interferons, and Their Receptors — 258Achsah D. Keegan, Warren J. Leonard10 Tumor Necrosis Factor Superfamily of Cytokines and Receptors — 308Carl F. Ware, Nancy H. Ruddle11 Chemokines and Chemokine Receptors — 344Philip M. Murphy Section IV. Innate Immunity12 Pattern Recognition Receptors and the IL- 1 Family — 386Rajendra Karki, Thirumala- Devi Kanneganti13 The Complement System — 416Erin E. West, Claudia Kemper14 Neutrophils — 455Andres Hidalgo, Mariana J. Kaplan15 Macrophages — 469Gwendalyn J. Randolph16 Mast Cells and Basophils — 487Mindy Tsai, Stephen J. Galli17 Eosinophils — 519Elizabeth A. Jacobsen, Hirohito Kita18 The Biology of Natural Killer Cells and Innate Lymphoid Cells — 537Vincent Peng, Marco Colonna Section V. Adaptive Immunity19 The Major Histocompatibility Complex — 573David H. Margulies, Kannan Natarajan, Jamie Rossjohn, James McCluskey20 Classical Antigen Processing and Presentation — 622Jonathan W. Yewdell, Paul Roche, Laurence C. Eisenlohr21 Immunoglobulins: Structure and Function — 644Mohamed Khass, David Wald, Neil S. Greenspan, Harry W. Schroeder, Jr22 Immunoglobulins: Molecular Genetics — 671Sebastian D. Fugmann23 T Cell Antigen Receptors and Antigen Recognition — 702Mark M. Davis, Yueh- Hsiu Chien24 Antigen Receptor Signaling — 734Nevil J. Singh, Gideon Wolf 25 B Cell Development in Mice — 774Nicole Baumgarth26 B Cell Responses — 798Claude- Agnès Reynaud, Jean- Claude Weill27 T Cell Development in the Thymus — 823Avinash Bhandoola, Remy Bosselut, Yousuke Takahama28 CD4+ Helper T Cells: Differentiation, Flexibility, and Heterogeneity — 856John J. O’Shea, Marion Pepper, Marc K. Jenkins, Danielle A. Chisolm29 Regulatory T Cells — 874Ethan M. Shevach30 CD8+ T Cell Memory — 924Francis R. Carbone, Thomas Gebhardt31 Cytotoxic Effector Functions — 944Morgan Huse Section VI. Integrative Immunology32 Immunologic Tolerance — 971Colin C. Anderson, Troy A. Baldwin, Peter A. Bretscher33 Fc Receptors and Their Role in Immune Regulation and Inflammation — 1008Jeffrey V. Ravetch, Aaron Gupta, Falk Nimmerjahn34 Dendritic cells — 1034Roxane Tussiwand, Pierre Guermonprez, Simon Yona35 Gamma Delta T Cells — 1054Adrian C. Hayday36 CD1- Restricted T Cells — 1102Pankaj Sharma, Florian Winau37 Mucosal- Associated Invariant T Cells and Other MR1- Reactive T Cells — 1137Sidonia B. G. Eckle, Wael Awad, Jamie Rossjohn, James McCluskey, Alexandra J. Corbett38 The Mucosal Immune System — 1178Yasmine Belkaid, Brian L. Kelsall, Warren Strober39 Introduction to Neuroimmunology — 1212Andrea Francesca Salvador, Jonathan Kipnis40 Vaccines — 1231Bali Pulendran41 Maternal- Fetal Immunology — 1283Gabrielle Rizzuto, Adrian Erlebacher Section VII. Immune Responses to Pathogens42 Response to Parasites — 1325David Sacks, Marion Pepper, Mary F. Fontana, P’ng Loke43 Immune Responses to Bacteria — 1355S. Celeste Morley, Moon H. Nahm44 Response to Viruses — 1399Hildegund C. J. Ertl45 Immunology of HIV Infection — 1445Gaurav D. Gaiha, Douglas S. Kwon Section VIII. Immunological Disease States and Immunodeficiency46 Autoimmunity and Autoimmune Diseases — 1465Gustaf Christoffersson, Ken T. Coppieters, Matthias von Herrath, Dirk Homann47 Immunologic Mechanisms of Allergic Disorders — 1515Stéphanie Lejeune, Kari C. Nadeau, David W. Scott, Joshua D. Milner48 Transplantation Immunology — 1549Megan Sykes, Anita S. Chong, Markus Y. Mapara49 Cancer Immunology and Immunotherapy — 1589Thomas F. Gajewski, Justin Kline50 Inborn Errors of Immunity — 1619
"Selected as a Doody's Core Title for 2022!Defining the field of immunology for 40 years, Paul's Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It's an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Reflects the latest advances in the field, including current insights on immune system function, both basic and translational. Contains 50 chapters written by leaders in all subfields of immunology. Provides extensive coverage of the molecular biology that explains the dynamics underlying immune disorders and their treatment. Includes 10 entirely new chapters covering invertebrate and plant immunity, eosinophils, innate lymphoid cells, gamma/delta T cells, NKT and MAIT cells, immunometabolism, maternal-fetal immunology and more. Contains abundant full-color illustrations and tables that provide essential information at a glance. Features annual updates from the authors to the VST version, keeping you current with changes in this dynamic field from the experts. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. "--
9781975142513
2022032189
MEDICAL / Immunology
MEDICAL / Infectious Diseases
Immune System Phenomena
RC585 / .P38 2023
616.97
QW 504