Zetech University Library - Online Catalog

Mobile: +254-705278678

Whatsapp: +254-706622557

Feedback/Complaints/Suggestions

library@zetech.ac.ke

Image from Google Jackets
Image from OpenLibrary

Transcriptomics and their importance / Sarah Naiyer, PhD (editor), Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA, Khalid Hussain Bhat, PhD (editor), Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir.

Contributor(s): Material type: TextTextSeries: Cell Biology Research Progress SerPublisher: New York : Nova Science Publishers, [2022]Description: 1 online resourceContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9798886972030
Subject(s): Genre/Form: Additional physical formats: Print version:: Transcriptomics and their importanceDDC classification:
  • 572.8/845 23/eng/20220831
LOC classification:
  • QH450.2
Online resources:
Contents:
Intro -- Contents -- Preface -- Acknowledgments -- List of Acronyms -- Part I. Introduction to Transcriptomics -- Chapter 1 -- The Nuts and Bolts in Transcriptomics -- Abstract -- 1. Introduction -- 2. History towards the Development of Transcriptomics -- 3. RNA Sequencing (RNA-Seq) -- 3.1. Advances in RNA-Seq -- 4. Computational Analysis of RNA Sequencing Data -- 4.1. Quality Control of Raw Data -- 4.2. Read Alignment and Transcript Assembly -- 4.3. Expression Quantification -- 4.4. Differential Expression Analysis -- Conclusion and Further Advancements in Transcriptomic Analysis
4. Transcriptomics and Its Role in Understanding Cellular Function -- 4.1. Understanding Host Pathogen Interactions -- 4.2. Disease Profiling and Pathogenesis -- Conclusion -- References -- Part II. Understanding Cancer with Transcriptomics -- Chapter 3 -- Transcriptomics in Basic Cancer Biology -- Abstract -- 1. History of Gene Expression Techniques-Brief Introduction -- 2. RNA-Based Therapeutics -- 2.1. Tumor Heterogeneity and RNA-seq -- 2.2. Transcriptomics in Clinical Classifications of Cancer -- 2.3. Identification of Cancer Biomarkers for Early Detection
3. Applications of RNA-Sequencing in Cancer Research -- 3.1. Cancer Variance and Adaptation -- 3.2. Cancer Drug Tolerance -- 3.3. Differential Gene Expression and Cancer Biomarkers -- 3.4. Cancer Immunotherapy -- 4. Application of Transcriptomics in Cancer Diagnostic -- 4.1. Breast Cancer -- 4.2. Colorectal Cancer -- 4.3. Lung Cancer -- 4.4. Prostate Cancer -- 4.5. Skin Cancer -- 4.6. Thyroid Cancer -- 5. Challenges and Limitations -- 5.1. Construction of Library -- 5.2. Cost vs Coverage -- 5.3. Bioinformatic Challenges -- Conclusion and Future Prospects -- References -- Chapter 4
Single-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance -- Abstract -- 1. Introduction -- 2. Role of CSCs in Tumor Heterogeneity: Impact on Cancer Progression and Drug Resistance -- 3. Application of Single-Cell Transcriptomics in CSCs -- 4. Role of Single-Cell Transcriptomics in Personalised Therapy -- 5. Limitation of SCT in CSCs Driven Cancer -- Conclusion and Future Prospects -- References -- Chapter 5 -- Transcriptome: A Tool for Precision Oncology -- Abstract -- 1. Introduction
Summary: "Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation"-- Provided by publisher.
Tags from this library: No tags from this library for this title. Log in to add tags.
No physical items for this record

Includes bibliographical references and index.

"Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation"-- Provided by publisher.

Description based on print version record and CIP data provided by publisher; resource not viewed.

Intro -- Contents -- Preface -- Acknowledgments -- List of Acronyms -- Part I. Introduction to Transcriptomics -- Chapter 1 -- The Nuts and Bolts in Transcriptomics -- Abstract -- 1. Introduction -- 2. History towards the Development of Transcriptomics -- 3. RNA Sequencing (RNA-Seq) -- 3.1. Advances in RNA-Seq -- 4. Computational Analysis of RNA Sequencing Data -- 4.1. Quality Control of Raw Data -- 4.2. Read Alignment and Transcript Assembly -- 4.3. Expression Quantification -- 4.4. Differential Expression Analysis -- Conclusion and Further Advancements in Transcriptomic Analysis

4. Transcriptomics and Its Role in Understanding Cellular Function -- 4.1. Understanding Host Pathogen Interactions -- 4.2. Disease Profiling and Pathogenesis -- Conclusion -- References -- Part II. Understanding Cancer with Transcriptomics -- Chapter 3 -- Transcriptomics in Basic Cancer Biology -- Abstract -- 1. History of Gene Expression Techniques-Brief Introduction -- 2. RNA-Based Therapeutics -- 2.1. Tumor Heterogeneity and RNA-seq -- 2.2. Transcriptomics in Clinical Classifications of Cancer -- 2.3. Identification of Cancer Biomarkers for Early Detection

3. Applications of RNA-Sequencing in Cancer Research -- 3.1. Cancer Variance and Adaptation -- 3.2. Cancer Drug Tolerance -- 3.3. Differential Gene Expression and Cancer Biomarkers -- 3.4. Cancer Immunotherapy -- 4. Application of Transcriptomics in Cancer Diagnostic -- 4.1. Breast Cancer -- 4.2. Colorectal Cancer -- 4.3. Lung Cancer -- 4.4. Prostate Cancer -- 4.5. Skin Cancer -- 4.6. Thyroid Cancer -- 5. Challenges and Limitations -- 5.1. Construction of Library -- 5.2. Cost vs Coverage -- 5.3. Bioinformatic Challenges -- Conclusion and Future Prospects -- References -- Chapter 4

Single-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance -- Abstract -- 1. Introduction -- 2. Role of CSCs in Tumor Heterogeneity: Impact on Cancer Progression and Drug Resistance -- 3. Application of Single-Cell Transcriptomics in CSCs -- 4. Role of Single-Cell Transcriptomics in Personalised Therapy -- 5. Limitation of SCT in CSCs Driven Cancer -- Conclusion and Future Prospects -- References -- Chapter 5 -- Transcriptome: A Tool for Precision Oncology -- Abstract -- 1. Introduction

Added to collection customer.56279.3

There are no comments on this title.

to post a comment.