Recent highlights in the discovery and optimization of crop protection products / edited by Peter Maienfisch, Sven Mangelinckx.

Based on key presentations given at the 14th International IUPAC conference on crop protection, May 19-24, 2019 Ghent, Belgium.

Preface -- 1. Recent innovation in crop protection research -- 2. Status and potential of bioprotection products for crop protection -- 3. Research and development of green pesticides in China -- 4. Agrochemical disease control: The story so far -- 5. Plant defense priming in the field: a review -- 6. Reaching beyond crop protection: Synergism between agricultural development and malaria eradication -- 7. Discovery and optimization of a novel insecticide, broflanilide -- 8. Studies on a novel insecticide, fluxametamide -- 9. The discovery of isocycloseram: A novel isoxazoline insecticide -- 10. Cyclaniliprole: A novel diamide insecticide -- 11. Optimization of mesoionic pyrido[1,2-a]pyrimidinone insecticides and discovery of 3-biaryl analogs controlling Lepidoptera species -- 12. Chemistry and biology connected: the development of Inscalis -- 13. Spiropidion discovery: Broad spectrum control of sucking insects and mites for multicrop utility -- 14. Discovery of oxazosulfyl: A novel broad-spectrum insecticide -- 15. Synthesis and biological activity of a novel insecticide, benzpyrimoxan -- 16. Discovery and optimization of silicon-containing complex II acaricides -- 17. Cycloclavine: A natural product with insecticidal potential -- 18. Photoresponsive pesticidal agents -- 19. Discovery and optimization of novel mosquitocidal compounds for the control of anopheline vectors of malaria -- 20. Antiparasitic dinitrile compounds for fly control in cattle -- 21. Design, structural derivation, and nematicidal activities of 1,2,3-benzotriazin-4-one derivatives -- 22. ADEPIDYN-the first N-methoxy-substituted carboxamide among the succinate dehydrogenase inhibitors -- 23. Isoflucypram-the next-generation succinate dehydrogenase inhibitor fungicide -- 24. Discovery and biological profile of inpyrfluxam: A new broad-spectrum succinate dehydrogenase inhibitor fungicide -- 25. Isofetamid: Discovery and optimization of a novel fungicide -- 26. Discovery of the trifluoromethyloxadiazoles-a new class of fungicides with a novel mode-of-action -- 27. The discovery of metyltetraprole: Reconstruction of the quinone outside inhibitor extended pharmacophore to overcome QoI-resistant strains -- 28. The discovery of florylpicoxamid, a new picolinamide for disease control -- 29. Discovery and validation of pesticide novel target: take pyruvate kinase as an example -- 30. Discovery and mode of action of cyclopyrimorate: A new paddy rice herbicide -- 31. Toward a mechanistic understanding of IGPD: A potential herbicide target -- 32. Isoxazolopyridines-a novel chemical cluster and a new (?) mode of action for dicot weed control -- 33. Quinazoline-2,4-dione: A promising scaffold for herbicide discovery -- 34. Tirexora -design of a new resistance breaking protoporphyrinogen IX oxidase inhibitor -- 35. Rinskor active herbicide-A new environment-friendly tool for weed management in rice and aquatic environments -- 36. Discovery of a novel uracil herbicide by using intermediate derivatization approach -- 37. Herbicidal activity and application of 1-(furan-2-yl)methylphosphonates as pyruvate dehydrogenase complex inhibitor against broadleaf weeds -- 38. Pesticide activities evaluation of b -carboline, dihydro-b -carboline, tetrahydro-b -carboline alkaloids, and their derivatives -- 39. Marine natural products and plant virus control -- 40. Design, synthesis, and biological evaluation of strigolactone derivatives for crop enhancement applications -- 41. Discovery and optimization of novel plant activators through structure-based virtual screening .

"This title highlights the most prominent, recent results in the search for safe and effective new crop protection products. With a focus on the design, synthesis, optimization and/or structure-activity relationships of new chemistries targeting insect, disease, weed, nematode, vector and animal parasite control, it also includes recent developments in crop enhancement chemistries and new approaches to crop protection products".