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001			on1343206393
003			OCoLC
005			20241121073047.0
006			m d
007			cr |||||||||||
008			220830s2022 nyu ob 001 0 eng
010			_a 2022040353
040			_aDLC _beng _erda _cDLC _dYDX _dOCLCF _dOCLCO _dN$T _dEBLCP _dOCLCQ
019			_a1348483812 _a1348491638
020			_a9798886972030 _q(electronic bk.)
020			_z9798886970449 _q(hardcover)
035			_a3344239 _b(N$T)
035			_a(OCoLC)1343206393 _z(OCoLC)1348483812 _z(OCoLC)1348491638
042			_apcc
050	0	0	_aQH450.2
082	0	0	_a572.8/845 _223/eng/20220831
049			_aMAIN
245	0	0	_aTranscriptomics and their importance / _cSarah Naiyer, PhD (editor), Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA, Khalid Hussain Bhat, PhD (editor), Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir.
263			_a2211
264		1	_aNew York : _bNova Science Publishers, _c[2022]
300			_a1 online resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aCell Biology Research Progress Ser.
504			_aIncludes bibliographical references and index.
520			_a"Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation"-- _cProvided by publisher.
588			_aDescription based on print version record and CIP data provided by publisher; resource not viewed.
505	0		_aIntro -- Contents -- Preface -- Acknowledgments -- List of Acronyms -- Part I. Introduction to Transcriptomics -- Chapter 1 -- The Nuts and Bolts in Transcriptomics -- Abstract -- 1. Introduction -- 2. History towards the Development of Transcriptomics -- 3. RNA Sequencing (RNA-Seq) -- 3.1. Advances in RNA-Seq -- 4. Computational Analysis of RNA Sequencing Data -- 4.1. Quality Control of Raw Data -- 4.2. Read Alignment and Transcript Assembly -- 4.3. Expression Quantification -- 4.4. Differential Expression Analysis -- Conclusion and Further Advancements in Transcriptomic Analysis
505	8		_a4. Transcriptomics and Its Role in Understanding Cellular Function -- 4.1. Understanding Host Pathogen Interactions -- 4.2. Disease Profiling and Pathogenesis -- Conclusion -- References -- Part II. Understanding Cancer with Transcriptomics -- Chapter 3 -- Transcriptomics in Basic Cancer Biology -- Abstract -- 1. History of Gene Expression Techniques-Brief Introduction -- 2. RNA-Based Therapeutics -- 2.1. Tumor Heterogeneity and RNA-seq -- 2.2. Transcriptomics in Clinical Classifications of Cancer -- 2.3. Identification of Cancer Biomarkers for Early Detection
505	8		_a3. Applications of RNA-Sequencing in Cancer Research -- 3.1. Cancer Variance and Adaptation -- 3.2. Cancer Drug Tolerance -- 3.3. Differential Gene Expression and Cancer Biomarkers -- 3.4. Cancer Immunotherapy -- 4. Application of Transcriptomics in Cancer Diagnostic -- 4.1. Breast Cancer -- 4.2. Colorectal Cancer -- 4.3. Lung Cancer -- 4.4. Prostate Cancer -- 4.5. Skin Cancer -- 4.6. Thyroid Cancer -- 5. Challenges and Limitations -- 5.1. Construction of Library -- 5.2. Cost vs Coverage -- 5.3. Bioinformatic Challenges -- Conclusion and Future Prospects -- References -- Chapter 4
505	8		_aSingle-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance -- Abstract -- 1. Introduction -- 2. Role of CSCs in Tumor Heterogeneity: Impact on Cancer Progression and Drug Resistance -- 3. Application of Single-Cell Transcriptomics in CSCs -- 4. Role of Single-Cell Transcriptomics in Personalised Therapy -- 5. Limitation of SCT in CSCs Driven Cancer -- Conclusion and Future Prospects -- References -- Chapter 5 -- Transcriptome: A Tool for Precision Oncology -- Abstract -- 1. Introduction
590			_aAdded to collection customer.56279.3
650		0	_aGenetic transcription. _921072
650		0	_aRNA editing. _921073
650		6	_aTranscription g�en�etique. _921074
650		6	_aARN _x�Edition. _921075
650		7	_aGenetic transcription _2fast _921072
650		7	_aRNA editing _2fast _921073
655		0	_aElectronic books. _93907
700	1		_aNaiyer, Sarah, _eeditor. _921076
700	1		_aBhat, Khalid Hussain, _eeditor. _921077
776	0	8	_iPrint version: _tTranscriptomics and their importance _dNew York : Nova Science Publishers, [2022] _z9798886970449 _w(DLC) 2022040352
830		0	_aCell Biology Research Progress Ser. _921078
856	4	0	_3EBSCOhost _uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3344239
938			_aYBP Library Services _bYANK _n18161649
938			_aEBSCOhost _bEBSC _n3344239
938			_aProQuest Ebook Central _bEBLB _nEBL30174205
938			_aAskews and Holts Library Services _bASKH _nAH40882319
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