000			03366cam a22005538i 4500
001			on1351659716
003			OCoLC
005			20241121073104.0
006			m d
007			cr |||||||||||
008			221115s2022 nyu ob 001 0 eng
010			_a 2022054766
040			_aDLC _beng _erda _cDLC _dYDX _dOCLCO _dN$T
020			_a8886974661 _q(electronic bk.)
020			_a9788886974660 _q(electronic bk.)
020			_a8886974663 _q(electronic bk.)
020			_a9798886974669 _q(electronic bk.)
020			_z9798886974089 _q(hardcover)
035			_a3452120 _b(N$T)
035			_a(OCoLC)1351659716
042			_apcc
050	0	0	_aQH599
082	0	0	_a572.8/7 _223/eng/20230118
049			_aMAIN
245	0	0	_aHMGB1 : _bfunctions, inhibitors and clinical significance / _cEylem Taskin, PhD (editor), Professor, Physiology, Adiyaman University, Adiyaman, Turkey, Celal Guven, PhD (editor), Associate Professor, Biophysics, Adiyaman University, Adiyaman, Turkey, Salih Tunc Kaya, PhD (editor), Assistant Dr., Biology, Duzce University, Duzce, Turkey.
263			_a2301
264		1	_aNew York : _bNova Science Publishers, _c[2022]
300			_a1 online resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	0		_aLife sciences research and development
504			_aIncludes bibliographical references and index.
520			_a"High mobility group box-1 (HMGB1) is one of the Damage-associated molecular patterns (DAMPs). HMGB1 plays plenty of role in both physiologic and pathophysiologic processes associated with its location, the receptor it binds to, and its redox form of its. Its functions are basically well known to have transcription factors, chemo-attractive effects, proinflammatory cytokine, neither chemokine nor cytokine effects, nor tissue repair function as well. This book provides an overview of the updated understanding of the dual role of HMGB1 in health and disease, such as cancer, myocardial ischemia/reperfusion injury, epilepsy, diabetes, multiple sclerosis, and neurodegenerative disease as well as hepatic steatosis and fatty liver disease been studied for years. That is why the modulation of HMGB1 might be a good candidate for the therapeutic of these diseases. Consequently, the present book comprises the role of HMGB1 in various pathologies and discusses its therapeutic potential in those pathologies"-- _cProvided by publisher.
588			_aDescription based on print version record and CIP data provided by publisher; resource not viewed.
590			_aAdded to collection customer.56279.3
650		0	_aChromatin _xMiscellanea. _921927
650		0	_aNervous system _xDiseases _xPathophysiology. _921928
650		6	_aChromatine _xMiscellan�ees. _921929
650		6	_aSyst�eme nerveux _xMaladies. _921930
700	1		_aTaskin, Eylem, _eeditor. _921931
700	1		_aGuven, Celal, _eeditor. _921932
700	1		_aKaya, Salih Tun�c, _eeditor. _921933
776	0	8	_iPrint version: _tHMGB1 _dNew York : Nova Science Publishers, [2022] _z9798886974089 _w(DLC) 2022054765
856	4	0	_3EBSCOhost _uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3452120
938			_aYBP Library Services _bYANK _n303275094
938			_aEBSCOhost _bEBSC _n3452120
994			_a92 _bN$T
999			_c8606 _d8606