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HMGB1 : functions, inhibitors and clinical significance / Eylem Taskin, PhD (editor), Professor, Physiology, Adiyaman University, Adiyaman, Turkey, Celal Guven, PhD (editor), Associate Professor, Biophysics, Adiyaman University, Adiyaman, Turkey, Salih Tunc Kaya, PhD (editor), Assistant Dr., Biology, Duzce University, Duzce, Turkey.

Contributor(s): Material type: TextTextSeries: Life sciences research and developmentPublisher: New York : Nova Science Publishers, [2022]Description: 1 online resourceContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 8886974661
  • 9788886974660
  • 8886974663
  • 9798886974669
Subject(s): Additional physical formats: Print version:: HMGB1DDC classification:
  • 572.8/7 23/eng/20230118
LOC classification:
  • QH599
Online resources: Summary: "High mobility group box-1 (HMGB1) is one of the Damage-associated molecular patterns (DAMPs). HMGB1 plays plenty of role in both physiologic and pathophysiologic processes associated with its location, the receptor it binds to, and its redox form of its. Its functions are basically well known to have transcription factors, chemo-attractive effects, proinflammatory cytokine, neither chemokine nor cytokine effects, nor tissue repair function as well. This book provides an overview of the updated understanding of the dual role of HMGB1 in health and disease, such as cancer, myocardial ischemia/reperfusion injury, epilepsy, diabetes, multiple sclerosis, and neurodegenerative disease as well as hepatic steatosis and fatty liver disease been studied for years. That is why the modulation of HMGB1 might be a good candidate for the therapeutic of these diseases. Consequently, the present book comprises the role of HMGB1 in various pathologies and discusses its therapeutic potential in those pathologies"-- Provided by publisher.
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Includes bibliographical references and index.

"High mobility group box-1 (HMGB1) is one of the Damage-associated molecular patterns (DAMPs). HMGB1 plays plenty of role in both physiologic and pathophysiologic processes associated with its location, the receptor it binds to, and its redox form of its. Its functions are basically well known to have transcription factors, chemo-attractive effects, proinflammatory cytokine, neither chemokine nor cytokine effects, nor tissue repair function as well. This book provides an overview of the updated understanding of the dual role of HMGB1 in health and disease, such as cancer, myocardial ischemia/reperfusion injury, epilepsy, diabetes, multiple sclerosis, and neurodegenerative disease as well as hepatic steatosis and fatty liver disease been studied for years. That is why the modulation of HMGB1 might be a good candidate for the therapeutic of these diseases. Consequently, the present book comprises the role of HMGB1 in various pathologies and discusses its therapeutic potential in those pathologies"-- Provided by publisher.

Description based on print version record and CIP data provided by publisher; resource not viewed.

Added to collection customer.56279.3

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